Description

n-α-Benzoyl-L-Arginine Ethyl Ester Hydrochloride is a high-purity, synthetic derivative of L-arginine, widely recognized as a specific chromogenic substrate for the serine protease trypsin. This compound is essential for biochemical research and industrial quality control, providing a reliable and sensitive method for enzymatic activity measurement. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies involved in protease studies and enzyme inhibitor screening.

Application

• Biochemical Research: As a specific chromogenic substrate for the kinetic assay and inhibition studies of trypsin and related serine proteases.
• Diagnostic Manufacturing: A key component in the formulation of diagnostic kits and reagents for measuring pancreatic function and protease activity in clinical samples.
• Pharmaceutical Development: Used in high-throughput screening (HTS) platforms to identify and evaluate potential trypsin inhibitors for therapeutic applications.
• Enzyme Characterization: For determining the specific activity, purity, and stability of trypsin preparations in industrial and laboratory settings.
• Quality Control: Employed in the QC laboratories of biotechnology and pharmaceutical companies to standardize enzyme-based processes and products.

Basic Information

Product Name	n-α-Benzoyl-L-Arginine Ethyl Ester Hydrochloride
CAS No.	971-21-1
Molecular Formula	C15H23N5O3 • HCl
Molecular Weight	357.84 g/mol
Synonyms	BAEE Hydrochloride; Nα-Benzoyl-L-arginine ethyl ester hydrochloride; Benzoyl arginine ethyl ester hydrochloride; L-BAEE HCl; Bz-Arg-OEt • HCl; Trypsin Substrate BAEE; N-α-Benzoyl-L-arginine ethyl ester monohydrochloride
EINECS	213-540-9

Quality Control

Our n-α-Benzoyl-L-Arginine Ethyl Ester Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, specific rotation for chiral integrity, and identity confirmation by IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term stability, consider storage under desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	[α]20/D: +15.0° to +18.0° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Solubility	Clear, colorless solution at 10 mg/mL in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.