Description

5-Aminolevulinic Acid, Hydrochloride Salt is a key biochemical precursor in the heme biosynthesis pathway. This compound is of significant commercial and research interest due to its role as a prodrug in photodynamic therapy and diagnostics. It is primarily utilized by the pharmaceutical, biotechnology, and agricultural research sectors for developing therapeutic agents, plant growth regulators, and biochemical studies.

Application

• Photodynamic Therapy (PDT): As a prodrug metabolized to protoporphyrin IX, a potent photosensitizer used in the treatment of actinic keratosis, basal cell carcinoma, and other dermatological conditions.
• Diagnostic Agent: Used for the fluorescence-guided detection and resection of malignant tissues, such as high-grade gliomas and bladder cancer.
• Agricultural Research: Employed in studies as a natural, biodegradable herbicide and plant growth regulator by inducing the accumulation of photodynamic porphyrins.
• Biochemical Research: Serves as a fundamental substrate in enzymatic studies of the tetrapyrrole biosynthesis pathway and related metabolic disorders.
• Cosmeceuticals: Investigated for use in topical formulations aimed at skin rejuvenation and acne treatment due to its effect on cellular metabolism.
• Veterinary Medicine: Applied in PDT for the treatment of superficial tumors in companion animals.

Basic Information

Product Name	5-Aminolevulinic Acid, Hydrochloride Salt
CAS No.	925-45-1
Molecular Formula	C5H9NO3 • HCl
Molecular Weight	167.59 (Free base) / 204.05 (HCl salt)
Synonyms	5-ALA HCl; δ-Aminolevulinic Acid Hydrochloride; 5-Amino-4-oxopentanoic Acid Hydrochloride; Levulinic acid, 5-amino-, hydrochloride; ALA HCl; 5-Aminolaevulinic Acid Hydrochloride; Aminolevulinic Acid HCl
EINECS	213-117-1

Quality Control

Our 5-Aminolevulinic Acid Hydrochloride is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and heavy metals to ensure it meets high-purity standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.