Description

Methacycline CAS NO 914-00-1 is a semi-synthetic, broad-spectrum tetracycline antibiotic derived from oxytetracycline. It is valued for its potent antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, mycoplasma, and certain protozoa. This compound is primarily utilized in pharmaceutical research and development, serving as a critical active pharmaceutical ingredient (API) for formulating antibacterial medications and as a reference standard in analytical laboratories.

Application

• Pharmaceutical API: Core active ingredient in the formulation of oral antibacterial capsules, tablets, and suspensions.
• Veterinary Medicine: Used in the treatment of bacterial infections in livestock and companion animals.
• Biomedical Research: A vital tool for studying bacterial protein synthesis inhibition and mechanisms of antibiotic resistance.
• Reference Standard: Serves as a high-purity calibrant in quality control laboratories for HPLC, UV, and microbiological assay methods.
• Microbiology: Incorporated into selective culture media for microbiological testing and diagnostic applications.

Basic Information

Product Name	Methacycline
CAS No.	914-00-1
Molecular Formula	C22H22N2O8
Molecular Weight	442.42 g/mol
Synonyms	Methacycline; 6-Methylene-5-hydroxytetracycline; 6-Methyleneoxytetracycline; Metacycline; Rondomycin; BRN 0092424; Adramycin; GS-2147; NSC-108164; Physiomycine
EINECS	213-018-4

Quality Control

Our Methacycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light yellow, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.