Description

(2α,17S,19E)-17-Acetoxy-19,20-Didehydroajmalan-16-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for the development of novel therapeutic agents, particularly in the fields of cardiovascular and neurological drug discovery. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of complex natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex indole alkaloids and potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with targeted biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the biosynthesis, metabolism, and biological pathways of related alkaloids.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing production processes for related compounds.

Basic Information

Product Name	(2α,17S,19E)-17-Acetoxy-19,20-Didehydroajmalan-16-Carboxylic Acid Methyl Ester
CAS No.	912-27-6
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	19,20-Didehydroajmalan-16-carboxylic acid, 17-(acetyloxy)-, methyl ester, (2α,17β,19E)-; Methyl (2α,17β,19E)-17-acetoxy-19,20-didehydroajmalan-16-carboxylate; 17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester; Ajmaline derivative; 19,20-Didehydro-17-acetoxyajmalan-16-methyl carboxylate
EINECS	Contact for details

Quality Control

Our (2α,17S,19E)-17-Acetoxy-19,20-Didehydroajmalan-16-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.