Description

D-Reticuline Hydrochloride is a high-purity, chiral benzylisoquinoline alkaloid salt, a critical intermediate in the biosynthesis of complex pharmaceuticals. Its primary commercial value lies in its role as a key chiral precursor for the synthesis of potent opioid analgesics and other bioactive compounds. This product is essential for research institutions and pharmaceutical manufacturers focused on developing and scaling up production of specialized active pharmaceutical ingredients (APIs) and investigating novel biosynthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the semi-synthesis of opioid analgesics such as morphine, codeine, and thebaine.
• Biochemical Research: Used in enzymatic and metabolic pathway studies to understand the biosynthesis of isoquinoline alkaloids in plants.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing laboratories.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical synthesis to create complex molecular architectures.
• Neuroscience Research: Investigated for its potential biological activity and interactions with neurological receptors in preclinical studies.

Basic Information

Product Name	D-Reticuline Hydrochloride
CAS No.	903-91-3
Molecular Formula	C19H23NO4 · HCl
Molecular Weight	365.85 g/mol
Synonyms	(+)-Reticuline Hydrochloride; (S)-Reticuline Hydrochloride; 1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinol Hydrochloride; Reticuline HCl; D-Reticuline HCl; NSC 407347; (S)-Reticuline HCl
EINECS	Contact for details

Quality Control

Our D-Reticuline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.