Description

Dl Normetanephrine CAS NO 97-31-4 is a synthetic catecholamine derivative, serving as a key intermediate and reference standard in biochemical research and pharmaceutical development. Its primary value lies in its role as a metabolite of norepinephrine, making it essential for studying adrenergic pathways and neurotransmitter metabolism. This compound is critically needed by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on neurochemistry and cardiovascular research.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (e.g., HPLC, LC-MS) in drug metabolism and pharmacokinetic (DMPK) studies.
• Biochemical Research: Acts as a crucial metabolite in research on the sympathetic nervous system, catecholamine biosynthesis, and degradation pathways.
• Diagnostic Reagent Manufacturing: Employed as a raw material in the production of immunoassay kits for the quantitative determination of normetanephrine in clinical samples (plasma, urine) to aid in the diagnosis of pheochromocytoma and paraganglioma.
• Neuropharmacology Studies: Utilized to investigate the mechanisms of action of drugs affecting adrenergic receptors and neurotransmitter reuptake.
• Academic & Clinical Research: Serves as a pure chemical entity for in-vitro and ex-vivo studies related to stress response, hypertension, and autonomic nervous system disorders.
• Quality Control: Functions as an internal standard or system suitability compound in analytical laboratories to ensure the accuracy and precision of test results for related pharmaceutical products.

Basic Information

Product Name	Dl Normetanephrine
CAS No.	97-31-4
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	DL-Normetanephrine; (±)-Normetanephrine; 3,4-Dihydroxyphenyl ethanolamine methyl ether; 4-[2-(Methylamino)-1-hydroxyethyl]benzene-1,2-diol; DL-3-O-Methylnoradrenaline; DL-3-Methoxy norepinephrine; DL-α-(Aminomethyl)-3-hydroxy-4-methoxybenzyl alcohol; DL-4-Hydroxy-3-methoxyphenylethanolamine
EINECS	202-576-8

Quality Control

Our Dl Normetanephrine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and light-sensitive, prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.