Description

Lobeline is a natural alkaloid derived from plants of the *Lobelia* genus, recognized for its pharmacological activity as a nicotinic acetylcholine receptor partial agonist. This compound is valued for its role in research and development, particularly in the study of neurological pathways and respiratory function. It serves as a critical reference standard and intermediate for pharmaceutical, nutraceutical, and academic research sectors seeking high-purity bioactive molecules.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in studies targeting smoking cessation, neurological disorders, and respiratory stimulants.
• Biochemical Research: Used in *in vitro* and *in vivo* studies to investigate nicotinic receptor mechanisms, neurotransmitter release, and neuronal signaling pathways.
• Nutraceutical Formulations: Employed as a key component in the development of specialized dietary supplements focused on respiratory support.
• Academic & Clinical Studies: Serves as a crucial compound for pharmacological profiling, toxicity studies, and mechanism-of-action research in university and institutional labs.
• Chemical Synthesis: Acts as a sophisticated building block or precursor for the synthesis of novel analogs and derivatives in medicinal chemistry.
• Quality Control Laboratories: Utilized as an analytical standard for the identification and assay of lobeline in raw materials and finished products.

Basic Information

Product Name	Lobeline
CAS No.	90-69-7
Molecular Formula	C22H27NO2
Molecular Weight	337.46 g/mol
Synonyms	Lobeline; α-Lobeline; L-Lobeline; (2R,6S)-2-[(2S)-2-Hydroxy-2-phenylethyl]-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidine; 2-[(2R)-2-Hydroxy-2-phenylethyl]-1-methyl-6-[(2S)-2-phenylethyl]piperidine; Lobelia Alkaloid; Inflatine; Lobidan
EINECS	202-012-6

Quality Control

Our Lobeline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.