Description

Lipoamido-Peg3-Azide CAS NO 890016-39-4 is a specialized heterobifunctional crosslinker featuring a lipoamide moiety, a triethylene glycol (PEG3) spacer, and a terminal azide group. This compound is engineered for precise bioconjugation, enabling the stable attachment of biomolecules, probes, or polymers via copper-free click chemistry with alkynes. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceutical development, proteomics, and advanced material science to create functionalized surfaces, drug delivery systems, and diagnostic tools.

Application

• Bioconjugation and Protein Labeling: Site-specific modification of proteins, antibodies, and peptides for therapeutic or diagnostic applications.
• Surface Functionalization: Immobilization of biomolecules onto nanoparticles, biosensors, and microarray slides for assay development.
• Polymer Chemistry: Synthesis of functionalized PEG-based polymers and hydrogels for controlled drug release and tissue engineering scaffolds.
• Chemical Biology Probes: Development of activity-based probes for studying enzyme function and metabolic pathways.
• Antibody-Drug Conjugate (ADC) Linker Exploration: Used in the research and development of novel linker technologies for targeted cancer therapies.
• Lipid Nanoparticle (LNP) Modification: Functionalization of lipid-based delivery systems for nucleic acids (e.g., mRNA, siRNA).

Basic Information

Product Name	Lipoamido-Peg3-Azide
CAS No.	890016-39-4
Molecular Formula	C17H31N5O5S2
Molecular Weight	449.58 g/mol
Synonyms	6,8-Bis(azidoethoxy)-N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)octanamide; Lipoic acid-PEG3-azide; α-Lipoic acid-PEG3-N3; Thioctic acid-PEG3-azide; Azido-PEG3-lipoamide; 5-(1,2-Dithiolan-3-yl)-N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)pentanamide-PEG3; N-(2-(2-(2-Azidoethoxy)ethoxy)ethyl)-5-((R)-1,2-dithiolan-3-yl)pentanamide
EINECS	Contact for details

Quality Control

Our Lipoamido-Peg3-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.