Description

Epiberberine (Chloride) is a high-purity, bioactive alkaloid compound derived from natural sources. This compound is of significant interest for its role as a key reference standard and active pharmaceutical ingredient in advanced research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and life science research industries for applications in metabolic studies, quality control, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of berberine-related products in pharmacopoeial methods (e.g., HPLC, LC-MS).
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of novel drugs targeting metabolic disorders.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms related to glucose metabolism, insulin signaling, and AMPK activation pathways.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements focused on metabolic health and wellness support.
• Quality Control & Assurance: Essential for analytical laboratories to calibrate equipment and validate methods for herbal extract analysis.

Basic Information

Product Name	Epiberberine (Chloride)
CAS No.	889665-86-5
Molecular Formula	C₂₀H₁₈ClNO₄
Molecular Weight	371.81 g/mol
Synonyms	Epiberberine chloride; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride; (13aS)-2,3,9,10-Tetramethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizinium chloride; Berberine, epi- (chloride); Natural Yellow 18 derivative; Isoberberine chloride (related isomer); Jatrorrhizine analog
EINECS	Contact for details

Quality Control

Our Epiberberine (Chloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent control of residual solvents and heavy metals. We provide Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with relevant standards for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.