Description

Biotin-Slc-Nhs CAS NO 887628-40-2 is a high-purity, amine-reactive biotinylation reagent designed for advanced biochemical conjugation. This compound is critical for creating stable, site-specific biotin-labeled probes used in affinity capture and detection systems. It is an essential tool for researchers and manufacturers in the fields of proteomics, diagnostics, and biopharmaceutical development who require reliable and efficient protein or antibody labeling.

Application

• Antibody Biotinylation: For preparing detection reagents in ELISA, flow cytometry, and immunohistochemistry (IHC) assays.
• Protein Labeling & Pull-Down Assays: Enables the immobilization of proteins onto streptavidin/avidin resins for affinity purification and interaction studies.
• Diagnostic Kit Manufacturing: Used in the production of lateral flow assays and other point-of-care diagnostic devices that utilize biotin-streptavidin technology.
• Cell Surface Labeling: For tagging membrane proteins in live-cell imaging and fluorescence-activated cell sorting (FACS) applications.
• Nucleic Acid Probe Conjugation: Facilitates the biotinylation of oligonucleotides for use in microarray and in-situ hybridization techniques.
• Drug Delivery System Development: Serves as a linker molecule in the design of targeted therapeutic conjugates.

Basic Information

Product Name	Biotin-Slc-Nhs
CAS No.	887628-40-2
Molecular Formula	C₂₀H₃₀N₄O₇S
Molecular Weight	470.54 g/mol
Synonyms	Biotin-SLC-NHS ester; Biotinamidocaproyl-6-aminohexanoic acid N-hydroxysuccinimide ester; Biotin-XX, SE; Biotin-LC-LC-NHS; EZ-Link™ Biotin-XX, SE; (+)-Biotinyl-6-aminocaproyl-6-aminohexanoic acid N-succinimidyl ester; N-Succinimidyl 6-((6-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)amino)hexanoyl)amino)hexanoate
EINECS	Contact for details

Quality Control

Our Biotin-Slc-Nhs is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the stringent requirements for research and diagnostic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.