Description

n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Erythro-Sphingosylphosphorylcholine is a sophisticated, fluorescently labeled sphingolipid derivative designed for advanced research applications. This compound matters as a critical tool for the real-time visualization and tracking of sphingolipid metabolism, membrane dynamics, and intracellular signaling pathways. Researchers in lipidomics, cell biology, and fluorescence microscopy require this high-purity probe to investigate complex biological processes with precision.

Application

• Fluorescent Cell Membrane Labeling: Used as a vital probe for staining and imaging plasma membranes and intracellular lipid structures in live-cell and fixed-cell microscopy.
• Sphingolipid Trafficking Studies: Enables the tracking of sphingolipid uptake, metabolism, and intracellular transport dynamics in real time.
• Lipid Raft and Microdomain Research: Serves as a key reagent for studying the organization and function of lipid rafts and membrane microdomains.
• Apoptosis and Cell Signaling Pathways: Applied in research focused on the role of sphingolipids in programmed cell death and signal transduction mechanisms.
• Model Membrane Systems: Incorporated into liposomes and artificial membranes to study biophysical properties and lipid-protein interactions.
• High-Content Screening (HCS): Utilized in automated imaging platforms for drug discovery campaigns targeting lipid-related diseases.

Basic Information

Item	Detail
Product Name	n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Erythro-Sphingosylphosphorylcholine
CAS No.	886209-09-2
Molecular Formula	C45H78BF2N4O7P
Molecular Weight	882.90 g/mol
Synonyms	BODIPY® FL C12-Sphingomyelin; BODIPY FL C12-Sphingomyelin; Fluorescent Sphingomyelin Analog; BODIPY® 500/510 C12-Sphingomyelin; 1-Oleoyl-2-{6-[(4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)hexanoyl]}-sn-glycero-3-phosphocholine (related structural analog); TopFluor® Sphingomyelin; N-{11-[4,4-Difluoro-5-(2-thienyl)-4-bora-3a,4a-diaza-s-indacene-3-yl]undecanoyl}sphingosylphosphorylcholine
EINECS	Contact for details

Quality Control

This high-value biochemical is manufactured under strict quality control protocols to ensure batch-to-batch consistency and optimal performance. Each lot is characterized using advanced analytical techniques including HPLC, mass spectrometry, and NMR to confirm identity, purity, and fluorescent properties. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Solutions prepared in appropriate solvents should be used immediately or stored according to established laboratory protocols for light-sensitive reagents.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Excitation/Emission Maxima	~500 nm / ~510 nm
Solubility	Soluble in chloroform, DMSO, DMF; forms micelles in aqueous buffer
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.