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β-D-Galnac-Peg4-Azide CAS NO 879004-92-9
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CAS No.:879004-92-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
β-D-Galnac-Peg4-Azide is a high-purity, functionalized carbohydrate derivative designed for advanced bioconjugation and chemical biology applications. This compound is critical for researchers and manufacturers requiring precise, site-specific labeling and crosslinking of biomolecules, particularly in the development of targeted therapeutics and diagnostic probes. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and academic institutions focused on glycobiology, antibody-drug conjugate (ADC) development, and proteomics.
Application
- Bioconjugation Reagent: Key building block for the site-specific modification of proteins, antibodies, and other biomolecules via copper-free click chemistry.
- Antibody-Drug Conjugate (ADC) Development: Enables the controlled attachment of cytotoxic payloads to targeting antibodies for cancer therapy.
- Glycobiology Research: Used as a tool compound to study glycan-protein interactions, cell surface labeling, and metabolic glycoengineering.
- Diagnostic Probe Synthesis: Facilitates the creation of fluorescent or radioactive probes for imaging and detection assays.
- Polymer and Material Science: Serves as a functional monomer or crosslinker for creating smart biomaterials and hydrogels with bioactive properties.
- Chemical Library Synthesis: Employed in the combinatorial synthesis of glycomimetics and carbohydrate-based drug candidates.
Basic Information
| Product Name | β-D-Galnac-Peg4-Azide |
| CAS No. | 879004-92-9 |
| Molecular Formula | C₂₃H₄₁N₅O₁₂ |
| Molecular Weight | 579.60 g/mol |
| Synonyms | N-Azidoacetylgalactosamine tetraethylene glycol; GalNAc-PEG4-N3; 2-Acetamido-2-deoxy-β-D-galactopyranosyl-(1→)-[11-azido-3,6,9-trioxaundecanyl]; Azido-PEG4-GalNAc; β-D-GalNAc-(1→O)-(CH₂CH₂O)₄-CH₂CH₂-N₃; N-(Azido-PEG4)-D-galactosamine; N-Acetyl-D-galactosamine-PEG4-azide; 1-O-[2-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethoxy)ethyl]-2-acetamido-2-deoxy-β-D-galactopyranose |
| EINECS | Contact for details |
Quality Control
Every batch of β-D-Galnac-Peg4-Azide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and Mass Spectrometry analysis. Our quality commitment aligns with the standards expected for research and pharmaceutical intermediate applications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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