Description

Dalasetron (Mesylate Hydrate) is a selective serotonin 5-HT3 receptor antagonist, supplied as its mesylate hydrate salt. This compound is critical for its potent antiemetic properties, effectively preventing nausea and vomiting. It is primarily utilized in pharmaceutical research and development for creating advanced therapeutic formulations.

Application

• Pharmaceutical Active Ingredient (API) for antiemetic drug formulations.
• Biochemical Research as a selective 5-HT3 receptor antagonist in neurological and pharmacological studies.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Preclinical Development for investigating new therapeutic applications targeting serotonin pathways.
• Process Chemistry as a key intermediate in the synthesis of more complex therapeutic agents.

Basic Information

Product Name	Dalasetron (Mesylate Hydrate)
CAS No.	878143-33-0
Molecular Formula	C20H27N3O2 • CH4O3S • xH2O
Molecular Weight	Contact for details
Synonyms	Dalasetron Mesylate Hydrate; Dalasetron Methanesulfonate Hydrate; (3aS)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4-tetrahydro-1H-pyrrolo[3,2-b]quinolin-1-one methanesulfonate hydrate; 5-HT3 Receptor Antagonist Dalasetron; BRL-43694 (Mesylate Hydrate)
EINECS	Contact for details

Quality Control

Our Dalasetron (Mesylate Hydrate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	As per batch COA
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm
Related Substances (HPLC)	Total impurities <2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.