Description

1,2-Ethanediamine, 1,2-Bis(4-Methylphenyl)-, (1R,2R)- is a chiral diamine compound of significant interest in advanced organic synthesis. Its value lies in its rigid, enantiomerically pure structure, which makes it an excellent chiral building block and ligand for asymmetric catalysis. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• Chiral Ligand in Asymmetric Catalysis: Used to construct metal-complex catalysts for enantioselective hydrogenation, alkylation, and other key synthetic transformations.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of enantiomerically pure drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Resolution Agent: Employed for the chiral separation of racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with specific chiral or structural properties.
• Fine Chemical Synthesis: A key precursor in the multi-step synthesis of complex natural products, agrochemicals, and performance materials.

Basic Information

Product Name	1,2-Ethanediamine, 1,2-Bis(4-Methylphenyl)-, (1R,2R)-
CAS No.	872595-06-7
Molecular Formula	C₁₈H₂₄N₂
Molecular Weight	268.40 g/mol
Synonyms	(1R,2R)-1,2-Bis(4-methylphenyl)ethane-1,2-diamine; (R,R)-1,2-Bis(p-tolyl)ethylenediamine; (1R,2R)-(-)-1,2-Di-p-tolylethylenediamine; (R,R)-DIPTEN; (R,R)-DTEN; (R,R)-1,2-Bis(4-methylphenyl)-1,2-ethanediamine; (R,R)-p-Tolyl Ethylenediamine; Chiral Diamine Ligand
EINECS	Contact for details

Quality Control

Our chiral diamine products are manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by Chiral HPLC to confirm enantiomeric excess (ee) and undergoes comprehensive analysis including ¹H/¹³C NMR and optical rotation measurement. A detailed Certificate of Analysis (COA) specifying purity, chiral purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation [α]₂₀D	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.