Description

Trabodenoson CAS NO 871108-05-3 is a highly selective adenosine A1 receptor agonist, representing a significant class of pharmaceutical intermediates and research compounds. This compound is crucial for the development of novel therapeutic agents targeting conditions related to adenosine receptor modulation. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and academic institutions engaged in cardiovascular, ophthalmic, and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced drug candidates targeting adenosine A1 receptors.
• Preclinical Research: Used in in vitro and in vivo studies to investigate the physiological effects of A1 receptor activation.
• Ophthalmic Drug Development: A critical component in research for developing treatments to reduce intraocular pressure, such as for glaucoma.
• Cardiovascular Research: Employed in studies exploring cardioprotective effects, including ischemia-reperfusion injury and atrial fibrillation.
• Metabolic Disorder Studies: Investigated for potential applications in managing conditions like diabetic nephropathy.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Trabodenoson
CAS No.	871108-05-3
Molecular Formula	C15H18N6O2
Molecular Weight	314.35 g/mol
Synonyms	INW-051; 2-[(6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl)amino]-3-(4-propoxyphenyl)propan-1-ol; Trabodenoson; Trabodenoson (INW-051); (2R)-2-[[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]amino]-3-(4-propoxyphenyl)propan-1-ol; A 1 Adenosine Receptor Agonist INW-051
EINECS	Contact for details

Quality Control

Our Trabodenoson is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and identification by spectroscopic methods (IR, NMR, MS), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C, in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.