Description

Cholesteryl n-(16-o-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)Carbamate is a sophisticated, high-purity synthetic intermediate designed for advanced research and development. This compound is critical for applications requiring precise molecular conjugation, particularly in the synthesis of complex biomolecules and delivery systems. It is primarily utilized by pharmaceutical researchers, bioconjugation specialists, and developers of novel drug delivery platforms.

Application

• Lipid Nanoparticle (LNP) Synthesis: A key building block for constructing ionizable cationic lipids used in mRNA and siRNA delivery systems.
• Bioconjugation Chemistry: Enables the site-specific attachment of cholesterol moieties to peptides, proteins, or oligonucleotides to enhance membrane affinity and cellular uptake.
• Pharmaceutical Research: Serves as a critical intermediate in the development of prodrugs and targeted therapeutic agents.
• Advanced Material Science: Used in the creation of functionalized polymers and smart materials for biomedical applications.
• Diagnostic Reagent Development: Facilitates the labeling of probes and contrast agents for imaging and diagnostic assays.

Basic Information

Product Name	Cholesteryl n-(16-o-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)Carbamate
CAS No.	869354-69-8
Molecular Formula	C71H106N2O11
Molecular Weight	1163.6 g/mol
Synonyms	Cholesteryl-PEG4-DMT Amine; Cholesterol-PEG4-DMT; DMT-Cholesterol-PEG4-Carbamate; 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-Hexadecahydro-1-[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 16-[(4,4'-dimethoxytrityl)oxy]-15-oxo-4,7,10,13-tetraoxa-2-azahexadec-1-oate
EINECS	Contact for details

Quality Control

Our Cholesteryl n-(16-o-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)Carbamate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and light-sensitive nature. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.