Description

n-D-(+)-Biotinyl-4,7,10,13,16-Pentaoxa-1,19-Diaminononadecane is a specialized, high-purity biotin derivative featuring a hydrophilic polyethylene glycol (PEG) spacer arm. This engineered structure is critical for creating stable conjugates, enhancing solubility, and facilitating targeted delivery in advanced bioconjugation applications. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors developing next-generation therapeutics and bioanalytical tools.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and peptides with biotin for detection or purification.
• Diagnostic Assay Development: Used in the synthesis of probes and components for ELISA, lateral flow assays, and other immunoassay platforms.
• Drug Delivery Systems: As a functional linker in the design of antibody-drug conjugates (ADCs) and targeted nanoparticle formulations.
• Affinity Chromatography: Synthesis of ligands for immobilization on avidin/streptavidin resins for the purification of biomolecules.
• Cell Surface Labeling: For tagging membrane proteins or receptors in flow cytometry and microscopy studies.
• Molecular Biology Reagents: Component in the production of labeled nucleotides, nucleic acid probes, and sequencing kits.

Basic Information

Product Name	n-D-(+)-Biotinyl-4,7,10,13,16-Pentaoxa-1,19-Diaminononadecane
CAS No.	869354-65-4
Molecular Formula	C29H55N5O9S
Molecular Weight	649.84 g/mol
Synonyms	Biotin-PEG5-amine; Biotin-PEG5-NH2; (+)-Biotinyl pentacosaethylene glycol) diamine; Biotinamidopentaoxanonadecanediamine; 5k-PEG-Biotin (amine terminated); Biotinylated PEG amine; EZ-Link Biotin-PEG5-Amine; PEG5 spacer biotin reagent
EINECS	Contact for details

Quality Control

Every batch of n-D-(+)-Biotinyl-4,7,10,13,16-Pentaoxa-1,19-Diaminononadecane is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.