Description

Rac-5-Phosphomevalonate Trilithium Salt is a high-purity biochemical intermediate essential for research in isoprenoid biosynthesis. This compound serves as a critical precursor in the mevalonate pathway, enabling the study of enzyme kinetics and metabolic regulation. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on metabolic engineering, drug discovery, and the development of novel therapeutic agents.

Application

• Enzymology Research: Used as a substrate for studying the activity and inhibition of key enzymes in the mevalonate pathway, such as mevalonate kinase and phosphomevalonate kinase.
• Metabolic Pathway Analysis: A vital tool for investigating the regulation and flux of the isoprenoid biosynthesis pathway in various biological systems.
• Pharmaceutical Development: Serves as a key intermediate in the research and development of drugs targeting cholesterol synthesis, bone disorders, and certain cancers.
• Biocatalyst and Fermentation Studies: Employed in metabolic engineering projects aimed at optimizing microbial production of isoprenoids, terpenes, and other high-value compounds.
• Biochemical Assay Standard: Used as a certified reference material in quantitative analytical methods like HPLC and LC-MS for pathway metabolite profiling.
• Academic & Educational Use: An important reagent for graduate-level teaching and laboratory experiments in advanced biochemistry and molecular biology courses.

Basic Information

Item	Detail
Product Name	Rac-5-Phosphomevalonate Trilithium Salt
CAS No.	868553-49-5
Molecular Formula	C6H9Li3O9P
Molecular Weight	287.93 g/mol
Synonyms	5-Phosphomevalonic Acid Trilithium Salt; (R,S)-5-Phosphomevalonic Acid Trilithium Salt; Mevalonate-5-Phosphate Trilithium Salt; PMA Trilithium Salt; (Rac)-5-Phosphomevalonic Acid Trilithium Salt; PVM Trilithium Salt; 3,5-Dihydroxy-3-methylpentanoic Acid 5-Phosphate Trilithium Salt
EINECS	Contact for details

Quality Control

Every batch of Rac-5-Phosphomevalonate Trilithium Salt is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure product integrity and traceability for research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Heavy Metals	< 10 ppm
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.