Description

Scopolamine Sulfate is a high-purity pharmaceutical-grade salt of the tropane alkaloid scopolamine. This compound is a critical active pharmaceutical ingredient (API) and intermediate valued for its potent anticholinergic and antiemetic properties. It is essential for manufacturers in the pharmaceutical and life sciences sectors, particularly for the production of medications to treat motion sickness, postoperative nausea, and for use in various research applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable solutions, transdermal patches (e.g., for motion sickness), and tablets.
• Antiemetic Formulations: Manufacture of medications to prevent and treat nausea and vomiting associated with surgery, chemotherapy, or motion.
• Anticholinergic Agent: Used in formulations to reduce secretions (e.g., before surgery) and to treat gastrointestinal spasms.
• Ophthalmic Solutions: Intermediate in the production of solutions used to dilate pupils (mydriasis) and for cycloplegic refractions.
• Biochemical Research: A standard compound in neurological and pharmacological research studying cholinergic receptors and pathways.
• Veterinary Medicine: Used in certain veterinary formulations for its sedative and antiemetic effects.

Basic Information

Product Name	Scopolamine Sulfate
CAS No.	866926-81-0
Molecular Formula	C17H21NO4 · H2SO4
Molecular Weight	399.42 g/mol (as sulfate salt)
Synonyms	Hyoscine Sulfate; Scopolamine Hydrobromide Sulfate Salt; (-)-Scopolamine Sulfate; 6β,7β-Epoxy-3α-tropanyl S-(-)-tropate Sulfate; L-Scopolamine Sulfate; Tropane-3α-ol, 6,7-epoxy-, sulfate, ester with (-)-tropic acid; Transderm Scop® API
EINECS	Contact for details

Quality Control

Our Scopolamine Sulfate is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against stringent specifications for identity, purity, and potency, with compliance to relevant pharmacopeial guidelines (e.g., USP, EP) where applicable. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-24° to -28° (c = 5 in H2O)
pH (1% Solution)	4.5 - 6.0
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.