Description

Tris-Nta CAS NO 862778-60-7 is a high-purity chemical compound, a derivative of nitrilotriacetic acid (NTA) functionalized with tris(hydroxymethyl)aminomethane (Tris). This specialized chelating agent is valued for its enhanced solubility and buffering capacity in aqueous systems. It is essential for researchers and manufacturers in life sciences, analytical chemistry, and industrial processes requiring precise metal ion control and stable pH conditions.

Application

• Biochemical Research & Buffer Systems: Used as a component in specialized biological buffers for protein purification, crystallization, and enzymatic assays.
• Analytical Chemistry & Chromatography: Serves as a mobile phase additive or chelating agent in HPLC and capillary electrophoresis to improve peak shape and separation of metal-sensitive analytes.
• Molecular Biology Reagents: Employed in the formulation of lysis buffers, nucleic acid purification kits, and PCR master mixes to sequester contaminating metal ions.
• Industrial Cleaning & Chelation: Acts as a key ingredient in advanced cleaning formulations and water treatment processes to control scale and inhibit metal-catalyzed degradation.
• Pharmaceutical Intermediate: Utilized in the synthesis of more complex chelating agents or as an excipient in specific drug delivery systems.
• Diagnostic Reagents: Incorporated into clinical diagnostic kits and assays where consistent metal chelation is critical for accurate results.

Basic Information

Product Name	Tris-Nta
CAS No.	862778-60-7
Molecular Formula	C9H18N2O9
Molecular Weight	298.25 g/mol
Synonyms	Tris-NTA; Tris Nitrilotriacetate; Tris(NTA); 2,2',2''-Nitrilotrisacetic acid tris(2-hydroxy-1,1-bis(hydroxymethyl)ethyl) ester; N,N-Bis(carboxymethyl)-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]glycine; Tris(hydroxymethyl)aminomethane nitrilotriacetate; TRIS-NTA chelator
EINECS	Contact for details

Quality Control

Our Tris-Nta is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.