Description

R-3,3'-Bis(4-(1,1-Dimethylethyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral organophosphorus compound that serves as a highly effective ligand and catalyst precursor in asymmetric synthesis. Its value lies in its ability to impart exceptional enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the production of high-purity chiral intermediates. This product is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with defined stereochemistry.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, including hydrogenation, cross-coupling, and allylic substitution.
• As a key component in catalyst systems for the enantioselective synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• For use in asymmetric organocatalysis, leveraging its Brønsted acid properties to activate substrates.
• In the research and development of novel agrochemicals and flavor/fragrance compounds requiring specific stereoisomers.
• As a reference standard and building block in methodological studies for new catalytic transformations in academic and industrial settings.

Basic Information

Product Name	R-3,3'-Bis(4-(1,1-Dimethylethyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	861909-30-0
Molecular Formula	C44H41O4P
Molecular Weight	664.77 g/mol
Synonyms	(R)-3,3'-Bis(4-tert-butylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-3,3'-Bis(4-tert-butylphenyl)-BINOL phosphate; (R)-DTB-BINOL phosphate; R-DTBBP; (R)-DTB-BINAPhosphate; (R)-3,3'-Di(4-tert-butylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; (R)-3,3'-Bis(4-(tert-butyl)phenyl)-[1,1'-binaphthalene]-2,2'-diyl hydrogen phosphate
EINECS	Contact for details

Quality Control

Our production of R-3,3'-Bis(4-(1,1-Dimethylethyl)Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity, critical for catalytic performance. Identity, purity (assay), and enantiomeric excess (ee) are rigorously verified using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.