Description

I3A CAS NO 849146-39-0 is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and other therapeutic areas. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug development and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Oncology Drug Research: Used in the development of targeted cancer therapies and investigational new drugs.
• Process Chemistry & Scale-up: Serves as a critical reagent for route scouting, optimization, and commercial manufacturing process development.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial drug substances.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: A starting material for the preparation of specialized derivatives and analogs for biological screening.

Basic Information

Product Name	I3A
CAS No.	849146-39-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	I3A; 1H-Indole-3-acetic acid, 5-(aminosulfonyl)-; 5-Sulfamoyl-1H-indole-3-acetic acid; 5-Sulfamoylindole-3-acetic acid; 849146-39-0; 5-(Aminosulfonyl)-1H-indole-3-acetic acid
EINECS	Contact for details

Quality Control

Our I3A is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.