Description

Acelarin CAS NO 840506-29-8 is a high-purity, synthetic chemical compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) for novel therapeutic agents, particularly in oncology. This product is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of targeted cancer therapies and other innovative medicines.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex drug molecules.
• Oncology Research: Used in the development and preclinical testing of new chemotherapeutic agents and targeted cancer treatments.
• Active Pharmaceutical Ingredient (API): Potential use as the core active component in formulated drug products under development.
• Process Development & Scale-up: Supports route scouting, optimization, and manufacturing process development for new chemical entities (NCEs).
• Reference Standard: Employed as an analytical standard for quality control, method development, and regulatory submissions.
• Biochemical Research: Utilized in studies investigating specific biochemical pathways and mechanisms of action.

Basic Information

Product Name	Acelarin
CAS No.	840506-29-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gemcitabine Elaidate; 5'-O-[((Z)-Octadec-9-enoyl)]gemcitabine; NUC-1031; ProGem; Pro-drug of Gemcitabine; (2R,3R,4R,5R)-2-(2,2-Difluoro-2H-1,3,2-oxazaphosphinan-2-yl)-5-[4-hydroxy-3,3-dimethyl-2-oxo-1-((Z)-octadec-9-enoyloxy)butyl]-3,4-dihydroxyoxolan-2-one 2-oxide
EINECS	Contact for details

Quality Control

Our Acelarin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by spectroscopic methods, and control of specified impurities to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.