Description

n-Palmitoyl-D31-D-Erythro-Sphingosylphosphorylcholine is a deuterated, isotopically labeled analog of sphingomyelin, a critical component of cell membranes and a key signaling molecule. This high-purity, chemically defined standard is essential for advanced analytical research requiring precise quantification and metabolic tracing. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for lipidomics, biomarker discovery, and drug metabolism studies.

Application

• Internal Standard for Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the accurate quantification of endogenous sphingomyelins and related metabolites in complex biological matrices via LC-MS/MS.
• Metabolic Pathway Tracing: Used in stable isotope labeling experiments (SIL) to investigate sphingolipid biosynthesis, turnover, and signaling pathways in cellular and animal models.
• Biomarker Research & Validation: Enables precise measurement of sphingomyelin species in clinical samples for the discovery and validation of disease biomarkers related to metabolic disorders, cancer, and neurodegeneration.
• Pharmaceutical R&D: Supports drug development efforts by studying drug-lipid interactions, membrane permeability, and the role of sphingolipids in disease mechanisms and therapeutic responses.
• Quality Control Reference Standard: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods in contract research organizations (CROs) and diagnostic kit manufacturing.
• Lipidomics & Systems Biology: A key reagent in comprehensive lipid profiling studies aimed at understanding global lipid changes under different physiological and pathological conditions.

Basic Information

Product Name	n-Palmitoyl-D31-D-Erythro-Sphingosylphosphorylcholine
CAS No.	807617-46-5
Molecular Formula	C39H43D31N2O6P
Molecular Weight	~734.3 g/mol (for deuterated form)
Synonyms	D31-Sphingomyelin (d31-SM); Deuterated Sphingomyelin (d31); N-(hexadecanoyl-D31)-D-erythro-sphingosylphosphorylcholine; SM(d31); Perdeuterated Palmitoyl Sphingomyelin; LysoSM(d31) precursor; Isotopically Labeled Sphingomyelin; Sphingomyelin-d31; Lipid Internal Standard-d31
EINECS	Contact for details

Quality Control

Every batch of n-Palmitoyl-D31-D-Erythro-Sphingosylphosphorylcholine is manufactured and analyzed under strict quality protocols to ensure the highest standards of isotopic purity and chemical identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98% (Area %)
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.