Description

(15Z-Tetracosenoyl) Coenzyme A (Ammonium Salt) is a high-purity, chemically defined long-chain fatty acyl-CoA ester, a critical biochemical reagent for lipid metabolism research. This compound serves as a vital substrate and intermediate for studying key enzymatic processes, including fatty acid elongation, desaturation, and β-oxidation pathways. It is essential for researchers and manufacturers in the fields of biochemistry, metabolic disease research, and the development of lipid-based therapeutics.

Application

• Enzymology Research: As a specific substrate for studying the activity and kinetics of enzymes like elongases (ELOVL) and acyl-CoA synthetases.
• Lipid Metabolism Studies: Investigating the biosynthesis and breakdown of very long-chain fatty acids (VLCFAs) in cellular and in vitro models.
• Biomarker Development: Utilization in assay development for diagnosing peroxisomal disorders (e.g., Zellweger spectrum disorders) linked to VLCFA metabolism.
• Drug Discovery Screening: Serving as a key reagent in high-throughput screens for inhibitors or modulators of lipid metabolic enzymes as therapeutic targets.
• Nutritional Science: Research into the metabolic fate and effects of dietary very long-chain monounsaturated fatty acids.
• Reference Standard: Use as an analytical standard in LC-MS or HPLC methods for the quantification of acyl-CoA species in biological samples.

Basic Information

Product Name	(15Z-Tetracosenoyl) Coenzyme A (Ammonium Salt)
CAS No.	800376-90-3
Molecular Formula	C45H81N7O17P3S • xNH3
Molecular Weight	~1124.1 (Free acid)
Synonyms	(15Z)-Tetracos-15-enoyl-CoA; Nervonoyl-CoA; cis-15-Tetracosenoyl Coenzyme A; 15Z-Tetracosenoyl-CoA; CoA(24:1(15Z)); Nervonic Acyl-Coenzyme A; Nervonoyl-Coenzyme A; (Z)-15-Tetracosenoyl-CoA
EINECS	Contact for details

Quality Control

Our (15Z-Tetracosenoyl) Coenzyme A (Ammonium Salt) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high biochemical purity suitable for research applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.