Description

Lipoxin A4 is a potent, specialized pro-resolving lipid mediator (SPM) derived from arachidonic acid, playing a critical role in the active resolution of inflammation. Its unique biological activity makes it a valuable research tool and a compound of significant interest for therapeutic development. This high-purity compound is essential for researchers and developers in pharmaceutical R&D, immunology, and biochemistry focused on inflammation resolution pathways.

Application

• Biomedical Research: As a reference standard and active agent in studies of inflammation resolution, immune modulation, and cellular signaling pathways.
• Drug Discovery & Development: A key lead compound for developing novel anti-inflammatory and pro-resolving therapeutics targeting chronic inflammatory diseases.
• In Vitro & In Vivo Studies: Used in cell culture assays and animal models to investigate the mechanisms of Lipoxin A4 and its analogs.
• Analytical Standard: Serves as a high-purity standard for method development and validation in analytical techniques like HPLC and LC-MS.
• Biochemical Pathway Analysis: Essential for elucidating the biosynthesis and metabolic fate of lipoxins and related eicosanoids.

Basic Information

Product Name	Lipoxin A4
CAS No.	89663-86-5
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	LXA4; (5S,6R,15S)-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic Acid; 5(S),6(R),15(S)-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic Acid; Lipoxin A4 Methyl Ester (related derivative); 5S,6R,15S-LXA4; (5S,6R,15S)-LXA4
EINECS	Contact for details

Quality Control

Our Lipoxin A4 is produced under stringent conditions to ensure the highest standards of purity and biological activity, suitable for sensitive research applications. Each batch is supported by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and stability are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.