Description

Tosylate Of Tetraethylene Glycol Monobenzyl Ether is a specialized organic intermediate featuring a terminal tosylate leaving group and a tetraethylene glycol spacer linked to a benzyl ether. This compound matters for its role as a versatile building block in the synthesis of complex molecules, enabling the controlled introduction of polyether chains. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing drug conjugates, surfactants, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating polyethylene glycol (PEG) linkers for prodrugs and antibody-drug conjugates (ADCs).
• Polymer & Material Science: Used as a functional monomer or cross-linking agent in the production of specialty polymers, hydrogels, and non-ionic surfactants.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, pesticides, and plant growth regulators that benefit from polyether solubility modifiers.
• Chemical Research (R&D): A valuable reagent for organic synthesis, facilitating nucleophilic substitution reactions to attach various functional groups via the reactive tosylate group.
• Surface Modification: Employed to create functionalized surfaces or nanoparticles with specific hydrophilic properties for biomedical and diagnostic applications.

Basic Information

Product Name	Tosylate Of Tetraethylene Glycol Monobenzyl Ether
CAS No.	89346-82-7
Molecular Formula	C28H42O8S
Molecular Weight	538.70 g/mol
Synonyms	2-[2-[2-[2-(Benzyloxy)ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate; Tetraethylene Glycol Monobenzyl Ether Tosylate; Benzyltetraethylene Glycol Tosylate; p-Toluenesulfonic Acid 2-[2-[2-[2-(Benzyloxy)ethoxy]ethoxy]ethoxy]ethyl Ester; 4-Methylbenzenesulfonic Acid 8-(Benzyloxy)-3,6-dioxaoctyl Ester; Bn-TEG-OTs; Benzyl-PEG4-OTs
EINECS	Contact for details

Quality Control

Our Tosylate Of Tetraethylene Glycol Monobenzyl Ether is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with high-purity standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.