Description

4-Methylumbelliferyla-L-Idopyranosiduronicacidsodiumsalt is a specialized fluorogenic substrate used for the detection and quantification of specific enzymatic activity. This compound matters as a critical reagent in biochemical research and diagnostic assay development, offering high sensitivity and specificity. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic industries for studying glycosidase enzymes and developing high-throughput screening methods.

Application

• Enzymatic Substrate for Research: A key fluorogenic substrate for the study of α-L-iduronidase and related glycosidase enzymes in biochemical and cell biology research.
• Diagnostic Assay Development: Used in the development of sensitive fluorometric diagnostic kits for the detection of enzyme deficiencies, such as those associated with lysosomal storage disorders like Mucopolysaccharidosis I (MPS I).
• High-Throughput Screening (HTS): Employed in pharmaceutical and biotechnology labs for HTS campaigns to identify potential inhibitors or activators of specific glycosidases.
• Enzyme Kinetics & Characterization: Essential for determining kinetic parameters (Km, Vmax) and characterizing the activity of purified or recombinant enzymes.
• Quality Control in Biomanufacturing: Used as a process control reagent to monitor enzyme activity during the production of therapeutic proteins or gene therapies.
• Clinical Research Biomarker: Facilitates the measurement of enzymatic activity in patient samples for clinical research studies and biomarker validation.

Basic Information

Product Name	4-Methylumbelliferyla-L-Idopyranosiduronicacidsodiumsalt
CAS No.	89157-94-8
Molecular Formula	C16H15NaO10
Molecular Weight	390.27 g/mol
Synonyms	4-MU-α-L-Idopyranosiduronic acid sodium salt; 4-Methylumbelliferyl α-L-idopyranosiduronic acid sodium salt; α-L-Iduronidase substrate; 4-MU-α-L-IdoA sodium salt; 4-Methylumbelliferyl-α-L-iduronide sodium salt; Fluorogenic α-L-iduronidase substrate; Idursulfase substrate analog; MPS I enzyme substrate.
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyla-L-Idopyranosiduronicacidsodiumsalt is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance data. We adhere to relevant quality guidelines to support our customers' compliance needs in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Fluorogenic Activity	Conforms to performance standard
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.