Description

S-Dimethylarsino-Coenzyme A is a specialized biochemical reagent featuring a dimethylarsino group attached to the coenzyme A molecule. This compound is critical for researchers studying arsenic metabolism, enzyme mechanisms, and the biochemical pathways of organoarsenicals. It serves as a vital tool for biochemical and pharmaceutical research, particularly in the investigation of metabolic processes and the development of analytical methods. The product is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to arsenic biotransformation and detoxification pathways.
• Metabolite Standard: Serves as a certified reference standard for the identification and quantification of organoarsenic metabolites in biological and environmental samples via LC-MS or HPLC.
• Enzymology Studies: Essential for investigating the kinetics and mechanisms of enzymes like arsenite methyltransferase.
• Pharmaceutical Development: Applied in early-stage research for compounds targeting arsenic-related biochemical pathways.
• Toxicology Research: Utilized to study the metabolic fate and biological activity of dimethylated arsenicals in cellular and animal models.
• Analytical Method Development: Acts as a key calibrant for developing and validating sensitive analytical methods for arsenic speciation.

Basic Information

Item	Details
Product Name	S-Dimethylarsino-Coenzyme A
CAS No.	88978-30-7
Molecular Formula	C23H38N7O17P3S
Molecular Weight	869.56 g/mol
Synonyms	Dimethylarsino-CoA; Coenzyme A, S-(dimethylarsino)-; S-(Dimethylarsino)coenzyme A; Dimethylarsinous acid coenzyme A ester; DMAs-CoA; Arsenical Coenzyme A derivative
EINECS	Contact for details

Quality Control

Every batch of S-Dimethylarsino-Coenzyme A is produced and analyzed under stringent quality protocols to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting requirements of research and development laboratories. Certificates of Analysis (COA) detailing purity, assay results, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV or enzymatic assay)
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.