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Rac-3-Octadecanamido-2-Methoxypropan-1-Ol Phosphocholine CAS NO 88876-07-7


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CAS No.:88876-07-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rac-3-Octadecanamido-2-Methoxypropan-1-Ol Phosphocholine CAS NO 88876-07-7 is a synthetic phospholipid derivative, specifically a phosphocholine-substituted amido ether lipid. This compound is valued for its role as a key intermediate and functional material in advanced lipid-based formulations, offering unique amphiphilic properties. It is primarily sought by researchers and manufacturers in the pharmaceutical, cosmetic, and advanced material science sectors for developing drug delivery systems, biomimetic membranes, and specialty surfactants.

Application

  • Liposome and Nanoparticle Formulation: A critical building block for constructing stable liposomal bilayers and lipid nanoparticles (LNPs) used in targeted drug delivery and mRNA vaccine technology.
  • Biomimetic Membrane Research: Used in model membrane systems (e.g., vesicles, supported lipid bilayers) to study cell membrane properties, protein-lipid interactions, and membrane fusion processes.
  • Cosmetic Actives Carrier: Functions as an advanced emulsifier and penetration enhancer in high-end skincare products for the stable encapsulation and delivery of active ingredients.
  • Specialty Surfactant: Employed in niche applications requiring biocompatible and tunable surfactants, such as in diagnostic assays and biomedical device coatings.
  • Pharmaceutical Intermediate: Serves as a synthetic precursor for more complex phospholipid drugs and prodrugs, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name Rac-3-Octadecanamido-2-Methoxypropan-1-Ol Phosphocholine
CAS No. 88876-07-7
Molecular Formula C₂₇H₅₇N₂O₆P
Molecular Weight 536.73 g/mol
Synonyms 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphocholine (analog); 3-[(1-Oxooctadecyl)amino]-2-methoxypropyl 2-(trimethylammonio)ethyl phosphate; Lyso-PC(18:0/0:0) derivative; N-Stearoyl-2-methoxy-1-phosphocholine-3-propanolamine; Phosphatidylcholine analogue; Glycerophosphocholine amide ether; 2-Methoxy-3-octadecanamidopropyl phosphocholine; rac-Lyso-GPC(18:0)
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Quality Control

Our Rac-3-Octadecanamido-2-Methoxypropan-1-Ol Phosphocholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support development and cGMP-grade manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder or waxy solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥95.0%
Water Content (KF) ≤2.0%
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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