Description

Methyl(2S,3R)-2,4-Dibromo-3-Hydroxybutyrate is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and reactive bromo and hydroxy functional groups make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules, including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel, stereochemically defined pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances requiring specific stereocenters.
• Academic & Industrial Research: A valuable reagent in methodological development for stereoselective synthesis and catalysis studies.
• Peptidomimetics & Bioactive Molecule Construction: Utilized to introduce brominated hydroxybutyrate motifs into peptide backbones or other bioactive scaffolds.

Basic Information

Product Name	Methyl(2S,3R)-2,4-Dibromo-3-Hydroxybutyrate
CAS No.	88824-09-3
Molecular Formula	C5H8Br2O3
Molecular Weight	275.93 g/mol
Synonyms	(2S,3R)-Methyl 2,4-dibromo-3-hydroxybutyrate; (2S,3R)-2,4-Dibromo-3-hydroxybutyric acid methyl ester; Methyl (2S,3R)-2,4-dibromo-3-hydroxybutanoate; (2S,3R)-DHBM; L-threo-Methyl 2,4-dibromo-3-hydroxybutyrate
EINECS	Contact for details

Quality Control

Our Methyl(2S,3R)-2,4-Dibromo-3-Hydroxybutyrate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.