Description

(5α,5'α,8'β,12β,12'β,19α,19'α)-2,2',3,3',6,6',7,7'-Octadehydro-7,8'-Biaspidospermidine-3,3'-Dicarboxylic Acid Dimethyl Ester is a complex, high-purity bisindole alkaloid derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate in sophisticated organic synthesis, particularly for constructing intricate nitrogen-containing molecular frameworks. It is primarily required by pharmaceutical R&D and academic research laboratories focused on medicinal chemistry and natural product synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel alkaloid-based drug candidates and complex bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic targets, particularly in neurological and anticancer research.
• Natural Product Synthesis: Serves as a sophisticated precursor in the total or semi-synthesis of complex indole alkaloids and their analogs.
• Chemical Biology Probe Development: Utilized to create specialized molecular probes for studying enzyme mechanisms and biological pathways.
• Advanced Organic Synthesis: Employed in methodological development for challenging C-C and C-N bond-forming reactions due to its rigid, polycyclic structure.

Basic Information

Item	Details
Product Name	(5α,5'α,8'β,12β,12'β,19α,19'α)-2,2',3,3',6,6',7,7'-Octadehydro-7,8'-Biaspidospermidine-3,3'-Dicarboxylic Acid Dimethyl Ester
CAS No.	88761-30-2
Molecular Formula	C42H44N4O4
Molecular Weight	668.83 g/mol
Synonyms	7,8'-Biaspidospermidine-3,3'-dicarboxylic acid, 2,2',3,3',6,6',7,7'-octadehydro-, dimethyl ester, (5α,5'α,8'β,12β,12'β,19α,19'α)-; Dimethyl (5α,5'α,8'β,12β,12'β,19α,19'α)-2,2',3,3',6,6',7,7'-octadehydro-7,8'-biaspidospermidine-3,3'-dicarboxylate; Bisindole Alkaloid Derivative; Aspidosperma Alkaloid Intermediate
EINECS	Contact for details

Quality Control

Our (5α,5'α,8'β,12β,12'β,19α,19'α)-2,2',3,3',6,6',7,7'-Octadehydro-7,8'-Biaspidospermidine-3,3'-Dicarboxylic Acid Dimethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.