Description

Rifaximin is a semi-synthetic, non-systemic antibiotic belonging to the rifamycin class, specifically designed for targeted action within the gastrointestinal tract. Its primary value lies in its minimal systemic absorption, making it a critical therapeutic agent for managing bacterial infections localized to the gut. This product is essential for pharmaceutical manufacturers developing treatments for conditions such as traveler's diarrhea, hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D). We supply high-purity Rifaximin CAS NO 88747-56-2 to support global drug development and production.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of oral tablets and capsules for gastrointestinal infections.
• Key component in the treatment and prevention of traveler's diarrhea caused by non-invasive strains of Escherichia coli.
• Primary therapeutic agent for reducing the risk of overt hepatic encephalopathy recurrence in adults.
• Treatment for irritable bowel syndrome with diarrhea (IBS-D) in adult patients.
• Research and development of novel antibiotic formulations and combination therapies.
• Reference standard in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Rifaximin
CAS No.	88747-56-2
Molecular Formula	C43H51N3O11
Molecular Weight	785.89 g/mol
Synonyms	Rifaximina; Rifaximinum; L-105; Rifamycin L 105; Rifamycin SV 2-Aminomethylpyrrolidine Derivative; 4-Deoxy-4'-methylpyrido[1',2'-1,2]imidazo[5,4-c]rifamycin SV; Normix; Xifaxan; Rifagut; Spiraxin; (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26S,27S,28E)-5,6,21,23,25-Pentahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)benzofuro[4,5-e]pyrido[1,2-a]benzimidazole-1,15(2H)-dione, 25-Acetate
EINECS	Contact for details

Quality Control

Our Rifaximin is manufactured and tested under strict quality management systems. Each batch is analyzed to meet stringent specifications for pharmaceutical-grade active ingredients, with a focus on purity, impurity profiles, and microbiological quality. Certificates of Analysis (COA) are provided, detailing comprehensive testing via validated methods such as HPLC, and confirming compliance with relevant pharmacopeial standards (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15°C and 25°C (59°F and 77°F), in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Orange-red crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Water (Karl Fischer)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Microbial Enumeration	Meets USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.