Description

Vibriobactin CAS NO 88217-23-6 is a high-purity siderophore compound originally characterized from Vibrio cholerae. This molecule is of significant interest for its role in iron acquisition and as a model compound in microbial physiology and medicinal chemistry research. It serves as a critical research tool for scientists in microbiology, infectious disease, and bioinorganic chemistry, enabling studies on bacterial virulence and novel antimicrobial strategies.

Application

• Microbiological Research: Used as a reference standard and tool compound to study siderophore-mediated iron uptake mechanisms in Vibrio species and other bacteria.
• Infectious Disease Studies: Employed in research focused on bacterial pathogenesis, host-pathogen interactions, and the development of anti-virulence strategies targeting iron acquisition pathways.
• Bioinorganic Chemistry: Serves as a model ligand for investigating the coordination chemistry of iron(III) and the design of synthetic siderophore analogs.
• Antimicrobial Development: Acts as a starting point or competitor in assays for developing novel antibiotics or "Trojan horse" conjugates that exploit bacterial iron transport systems.
• Analytical Standard: Provides a certified reference material for the identification and quantification of vibriobactin in complex biological matrices using techniques like HPLC and LC-MS.
• Enzyme Inhibition Studies: Utilized in biochemical assays to study enzymes involved in siderophore biosynthesis (non-ribosomal peptide synthetases) as potential drug targets.

Basic Information

Product Name	Vibriobactin
CAS No.	88217-23-6
Molecular Formula	C₃₄H₄₇N₇O₉
Molecular Weight	697.79 g/mol
Synonyms	N-[2-[[2-[[2-[[(2,3-Dihydroxybenzoyl)amino]acetyl]amino]acetyl]amino]acetyl]-N5-hydroxy-N1-(3-hydroxybutyryl)-L-ornithine; Vibrio Cholerae Siderophore; 2-(2,3-Dihydroxybenzamido)-N-[2-[2-[2-[[(3R)-3-hydroxybutanoyl]amino]-5-(hydroxyamino)-5-oxopentylamino]-2-oxoethyl]amino]-2-oxoethyl]acetamide
EINECS	Contact for details

Quality Control

Our Vibriobactin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and determination of residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.