Description

1-o-(9Z)Octadecenyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a lysophosphatidylcholine (LPC) derivative with an oleyl chain. This compound is a critical biochemical reagent valued for its role in membrane research, drug delivery systems, and as a precursor in lipid synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require well-defined, high-quality lipid components for their formulations and studies.

Application

• Liposome & Nanoparticle Formulation: A key component for creating stable liposomal drug delivery vehicles and lipid nanoparticles (LNPs) for mRNA and gene therapies.
• Biochemical & Cell Biology Research: Used as a membrane fusogen, a signaling lipid intermediate, and a tool for studying lipid metabolism and cell membrane dynamics.
• Pharmaceutical Excipient: Employed as a solubilizing agent and permeation enhancer in topical and injectable formulations.
• Biomimetic Membrane Models: Serves as a building block for creating supported lipid bilayers (SLBs) and other in vitro membrane systems for biophysical studies.
• Diagnostic Reagent Production: Utilized in the manufacture of reagents for clinical diagnostics, particularly in assays involving lipid metabolism or membrane integrity.
• Cosmetic & Dermal Science: Incorporated into advanced cosmetic formulations for its skin-barrier repair and moisturizing properties.

Basic Information

Item	Detail
Product Name	1-o-(9Z)Octadecenyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No.	87907-66-2
Molecular Formula	C₂₆H₅₂NO₇P
Molecular Weight	521.67 g/mol
Synonyms	1-Oleoyl-2-hydroxy-sn-glycero-3-phosphocholine; Lyso-oleoylphosphatidylcholine; LPC(18:1); 1-(9Z-Octadecenoyl)-2-hydroxy-sn-glycero-3-phosphocholine; 1-Oleoyl-2-lyso-sn-glycero-3-phosphocholine; 1-Oleoyl-LPC; LysoPC(18:1(9Z)); Oleoyl lysophosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-o-(9Z)Octadecenyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and TLC for impurity profiling, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity (typically >98%), and critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Complies with structure
Identification (MS)	Complies with structure
Purity (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol, DMSO
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.