Description

N(2)-(4-n-Butylphenyl)-2'-Deoxyguanosine 5'-Triphosphate is a chemically modified nucleotide triphosphate, specifically a derivative of dGTP. This compound is critical for advanced biochemical research and development, particularly in applications requiring controlled nucleotide incorporation or specific molecular labeling. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, enzymology, and next-generation sequencing technology development.

Application

• Next-Generation Sequencing (NGS): Used as a modified substrate in sequencing-by-synthesis platforms to study polymerase kinetics or engineer novel enzymes.
• Enzymology Studies: Serves as a probe to investigate the substrate specificity and catalytic mechanisms of DNA polymerases and other nucleotide-processing enzymes.
• Molecular Probes & Diagnostics: Acts as a building block for synthesizing labeled nucleotides used in diagnostic assays and fluorescence-based detection systems.
• Antiviral & Anticancer Research: Investigated for its potential to inhibit viral polymerases or be incorporated into DNA to study mutagenic effects and therapeutic pathways.
• Bioconjugation & Chemical Biology: The butylphenyl moiety provides a handle for further chemical modification, enabling the creation of cross-linking agents or affinity tags.

Basic Information

Product Name	N(2)-(4-n-Butylphenyl)-2'-Deoxyguanosine 5'-Triphosphate
CAS No.	87782-05-6
Molecular Formula	C20H27N5O13P3
Molecular Weight	662.38 g/mol
Synonyms	N2-(4-n-Butylphenyl)-2'-deoxyguanosine-5'-triphosphate; N2-(p-Butylphenyl)-dGTP; Butylphenyl-dGTP; Modified dGTP; 2'-Deoxyguanosine-5'-triphosphate, N2-(4-butylphenyl)-; dGTP-N2-(4-butylphenyl); N2-(4-Butylphenyl)-2'-deoxyguanosine 5'-(tetrahydrogen triphosphate)
EINECS	Contact for details

Quality Control

Our N(2)-(4-n-Butylphenyl)-2'-Deoxyguanosine 5'-Triphosphate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.