Description

1-Hexadecyl-2-Deoxyglycerophosphoric Acid is a synthetic phospholipid derivative, specifically a lysophosphatidic acid analogue with a hexadecyl (cetyl) chain. This compound is valued for its role as a key intermediate and building block in advanced lipid research and synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel drug delivery systems, lipid-based therapeutics, and biomimetic membrane studies.

Application

• Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of complex phospholipids and prodrugs for targeted therapies.
• Lipid Nanoparticle (LNP) Formulation: Used as a component in the development of non-viral delivery vectors for mRNA, siRNA, and other nucleic acid therapeutics.
• Biomembrane Research: Employed in model membrane systems (e.g., liposomes, bilayers) to study membrane fluidity, protein-lipid interactions, and signaling pathways.
• Bioconjugation & Probe Development: Acts as a scaffold for attaching fluorescent tags, targeting ligands, or other functional groups for diagnostic and imaging applications.
• Cosmetic & Dermal Science: Investigated for its potential in enhancing skin barrier function and as an ingredient in advanced topical formulations.
• Biochemical Reagents: Supplied as a high-purity standard or reagent for enzymatic studies and lipid metabolism research.

Basic Information

Product Name	1-Hexadecyl-2-Deoxyglycerophosphoric Acid
CAS No.	87746-71-2
Molecular Formula	C22H47O6P
Molecular Weight	438.58 g/mol
Synonyms	1-Cetyl-2-deoxy-sn-glycero-3-phosphate; Hexadecyl 2-deoxy-sn-glycero-3-phosphate; 2-Deoxy-1-O-hexadecyl-sn-glycero-3-phosphoric acid; C16 LysoPA (2-deoxy); Lysophosphatidic Acid (2-deoxy, C16:0); 1-O-Hexadecyl-2-deoxy-sn-glycerol-3-phosphate; LPA(2-deoxy, 16:0); Phosphoric acid mono[(2R)-2-deoxy-3-(hexadecyloxy)-2-hydroxypropyl] ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a cGMP-compliant quality management system to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.