Description

Cytidine 5'-Diphosphate 2',3'-Dialdehyde is a chemically modified nucleotide derivative where the ribose sugar moiety has been oxidized to a dialdehyde. This compound serves as a critical biochemical research reagent and a versatile chemical intermediate for the synthesis of more complex nucleotide analogs and affinity probes. It is primarily utilized by pharmaceutical researchers, academic biochemists, and diagnostic kit manufacturers involved in enzymology, molecular biology, and the development of novel therapeutic agents.

Application

• Enzyme Inhibition Studies: Acts as a mechanism-based inhibitor or affinity label for ribonucleotide reductases and other nucleotide-dependent enzymes.
• Bioconjugation & Probe Synthesis: The reactive aldehyde groups enable covalent cross-linking to proteins, peptides, or other molecules for creating affinity purification resins or detection probes.
• Nucleic Acid Research: Used in the study of RNA structure, function, and metabolism, and as a precursor for synthesizing modified nucleoside triphosphates.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of antiviral and anticancer nucleotide analogs.
• Diagnostic Development: Employed in the design and manufacture of diagnostic assays that detect specific enzymatic activities or nucleotide-binding proteins.

Basic Information

Product Name	Cytidine 5'-Diphosphate 2',3'-Dialdehyde
CAS No.	87668-74-4
Molecular Formula	C9H13N3O12P2
Molecular Weight	417.16 g/mol
Synonyms	CDP-Dialdehyde; 2',3'-Dialdehyde Cytidine 5'-Diphosphate; Cytidine 5'-Diphospho-2',3'-dialdehyde; Periodate-oxidized CDP; Oxidized Cytidine Diphosphate; CDP-2',3'-dial; 5'-CDP-2',3'-dialdehyde
EINECS	Contact for details

Quality Control

Our Cytidine 5'-Diphosphate 2',3'-Dialdehyde is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. We provide comprehensive Certificates of Analysis (COA) upon request, detailing all relevant specifications to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.