Description

n-Hexadecanoyl-L-Homoserine Lactone is a high-purity, long-chain N-acyl homoserine lactone (AHL) quorum sensing signaling molecule. This compound is critical for researchers studying bacterial cell-to-cell communication, biofilm formation, and virulence factor regulation in Gram-negative bacteria. It is an essential tool for microbiologists, molecular biologists, and pharmaceutical developers working in academic research, antimicrobial discovery, and agricultural biotechnology.

Application

• Quorum Sensing Research: A key signaling molecule for studying intercellular communication in bacteria, particularly in Pseudomonas aeruginosa and other Gram-negative species.
• Biofilm Studies: Used to investigate and modulate biofilm formation and dispersion, relevant for combating persistent infections and biofouling.
• Antivirulence Strategy Development: Serves as a standard or inhibitor in screens for novel compounds that disrupt quorum sensing to attenuate bacterial pathogenicity.
• Agricultural Biotechnology: Applied in research to understand and potentially control plant-pathogen interactions mediated by bacterial signaling.
• Microbiome & Synthetic Biology: A fundamental component in engineering synthetic genetic circuits and studying microbial community dynamics.
• Pharmaceutical R&D: Utilized in the discovery and validation of new anti-infective agents that target bacterial communication pathways without applying direct growth pressure.

Basic Information

Item	Detail
Product Name	n-Hexadecanoyl-L-Homoserine Lactone
CAS No.	87206-01-7
Molecular Formula	C20H35NO4
Molecular Weight	353.50 g/mol
Synonyms	N-Hexadecanoyl-L-homoserine lactone; C16-HSL; N-(3-Oxotetradecanoyl)-L-homoserine lactone; N-Palmitoyl-L-homoserine lactone; 3-Oxo-N-hexadecanoylhomoserine lactone; AHL C16; N-Acyl homoserine lactone C16; Quorum sensing molecule C16
EINECS	Contact for details

Quality Control

Our n-Hexadecanoyl-L-Homoserine Lactone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for sensitive biological assays. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support research and development with materials produced to meet the exacting standards required for life science applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, ethanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.