Description

Aldosterone-3-(o-Carboxymethyl)Oximino-(2-Iodohistamine) is a key chemical derivative of the hormone aldosterone, specifically designed for advanced biochemical research and diagnostic applications. This compound is primarily valued for its role as a high-affinity hapten or tracer in the development of sensitive immunoassays, particularly for the quantification of aldosterone levels. It is an essential reagent for pharmaceutical R&D, clinical diagnostics, and endocrinology research, enabling precise measurement and study of mineralocorticoid activity. Global suppliers and research institutions rely on this high-purity intermediate to ensure the accuracy and reliability of their analytical methods.

Application

• Immunoassay Development: Critical hapten for the production of specific antibodies and tracers in competitive ELISA and RIA for aldosterone detection.
• Clinical Diagnostics: Used in the formulation of test kits for measuring aldosterone in serum, plasma, and urine to diagnose disorders like primary aldosteronism.
• Pharmaceutical Research: Serves as a key intermediate in the synthesis of novel radioligands and probes for studying mineralocorticoid receptor (MR) function and drug discovery.
• Biochemical Tracer: Employed as a labeled derivative (e.g., iodinated) in receptor-binding assays and other in vitro studies.
• Endocrinology Studies: A vital tool for research into hypertension, heart failure, and electrolyte balance mechanisms.
• Reference Standard: Can be utilized as a high-purity chemical reference material for method validation and quality control in analytical laboratories.

Basic Information

Product Name	Aldosterone-3-(o-Carboxymethyl)Oximino-(2-Iodohistamine)
CAS No.	87002-37-7
Molecular Formula	C27H35IN6O6
Molecular Weight	666.51 g/mol
Synonyms	Aldosterone-3-CMO-(2-Iodohistamine); 2-Iodohistamine Aldosterone-3-CMO Derivative; Aldosterone-3-(Carboxymethyl)oxime-2-Iodohistamine; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al 3-(O-Carboxymethyl)oxime 2-Iodohistamine; Aldosterone-3-CMO-Histamine(I); Aldosterone Hapten; Aldosterone Tracer; Aldosterone Derivative for Immunoassay
EINECS	Contact for details

Quality Control

Our Aldosterone-3-(o-Carboxymethyl)Oximino-(2-Iodohistamine) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive immunoassay applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and structural confirmation via MS and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting identity, purity, and related substance profiles. Our quality commitment aligns with the standards expected for research and diagnostic reagent manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.