Description

7,7-Azo-3-A,12-A-Dihydroxycholanic Acid CAS NO 86992-52-1 is a specialized bile acid derivative characterized by its unique azo-bridged structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key synthetic intermediate or a potential pharmacophore. It serves the needs of research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in developing novel therapeutic agents, especially those targeting metabolic or liver-related pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroidal drugs and bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies and enzyme interaction research.
• Medicinal Chemistry: Acts as a precursor for developing potential therapeutic agents targeting bile acid receptors (e.g., FXR, TGR5).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in universities and R&D labs for studying bile acid chemistry and derivatization.

Basic Information

Item	Detail
Product Name	7,7-Azo-3-A,12-A-Dihydroxycholanic Acid
CAS No.	86992-52-1
Molecular Formula	C₂₄H₃₈N₂O₆
Molecular Weight	450.57 g/mol
Synonyms	7,7'-Azobis(3α,12α-dihydroxy-5β-cholan-24-oic Acid); 3α,12α-Dihydroxy-7,7'-azocholanic Acid; Azo-Bridged Dihydroxycholanic Acid; 7,7-Azocholic Acid Derivative; 86992-52-1; 7,7'-Azo-lithocholic acid derivative
EINECS	Contact for details

Quality Control

Our production of 7,7-Azo-3-A,12-A-Dihydroxycholanic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation. We ensure traceability and consistency, with Certificates of Analysis (COA) provided for every shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.