Description

Iodoacetamidoerythrosin CAS NO 86583-16-6 is a specialized chemical derivative combining the structural motifs of erythrosin, a xanthene dye, with an iodoacetamide functional group. This compound is valued for its role as a versatile biochemical reagent, particularly in protein chemistry and proteomics research. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications such as protein labeling, enzyme inhibition studies, and the development of diagnostic assays.

Application

• Protein Labeling and Modification: Acts as an alkylating agent for specific cysteine residues in proteins, facilitating tracking and analysis.
• Enzyme Activity Studies: Used to investigate enzyme mechanisms and active site characterization through covalent inhibition.
• Bioconjugation: Serves as a linker for attaching fluorescent probes or other molecules to biomolecules for imaging and detection.
• Proteomics Research: Employed in mass spectrometry-based workflows for peptide and protein identification and quantification.
• Diagnostic Reagent Development: A component in the formulation of reagents for clinical and research diagnostic kits.
• Biochemical Research: Used as a tool compound in various laboratory studies involving thiol-reactive chemistry.

Basic Information

Product Name	Iodoacetamidoerythrosin
CAS No.	86583-16-6
Molecular Formula	C20H8I4Na2O9 (Disodium salt form)
Molecular Weight	Contact for details
Synonyms	Erythrosin iodoacetamide; Iodoacetamide Erythrosin; Erythrosin B iodoacetamide; 2',4',5',7'-Tetraiodo-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid iodoacetamide derivative; IAE; Iodoacetamido Erythrosin B; Reactive Red 4 iodoacetamide derivative
EINECS	Contact for details

Quality Control

Our Iodoacetamidoerythrosin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.