Description

3-Ketostearoyl-Coenzyme A is a key biochemical intermediate in fatty acid metabolism, specifically in the β-oxidation pathway. This high-purity compound is essential for research and development in metabolic studies and enzyme kinetics. It is primarily utilized by biochemists, pharmaceutical researchers, and diagnostic manufacturers working on lipid metabolism disorders, enzyme assays, and metabolic pathway analysis.

Application

• Biochemical Research: Used as a critical substrate in studies of mitochondrial β-oxidation and peroxisomal fatty acid degradation pathways.
• Enzyme Kinetics & Assay Development: Serves as a standard or substrate for characterizing acyl-CoA dehydrogenases and other enzymes involved in ketone body metabolism.
• Pharmaceutical R&D: Employed in target validation and screening for drugs aimed at metabolic diseases such as diabetes, obesity, and rare inherited metabolic disorders.
• Diagnostic Reagent Manufacturing: A potential component in enzymatic test kits for clinical diagnostics to measure specific metabolic enzyme activities.
• Academic Research: Fundamental tool for university and institutional labs investigating lipid biochemistry and cellular energy homeostasis.
• Metabolomics Studies: Used as a reference standard in LC-MS or GC-MS based metabolomic profiling to identify and quantify metabolic intermediates.

Basic Information

Product Name	3-Ketostearoyl-Coenzyme A
CAS No.	86370-20-9
Molecular Formula	C39H66N7O19P3S
Molecular Weight	1089.93 g/mol
Synonyms	3-Oxooctadecanoyl-CoA; 3-Oxostearoyl-Coenzyme A; 3-Ketooctadecanoyl-Coenzyme A; 3-Oxostearoyl-CoA; 3-Ketostearoyl-CoA; Coenzyme A, S-(3-oxooctadecanoate); 3-Oxooctadecanoyl-coenzyme A; 3-Ketooctadecanoyl-CoA
EINECS	Contact for details

Quality Control

Our 3-Ketostearoyl-Coenzyme A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation (NMR, MS) to ensure it meets the exacting standards required for biochemical research. A detailed Certificate of Analysis (COA) is provided, documenting purity, assay results, and impurity profiles. We support compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot into single-use vials to avoid repeated freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC, MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic/UV)	≥ 90% (CoA content)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.