Description

11-Hydroxydocosahexaenoate is a specialized hydroxylated derivative of the essential ω-3 fatty acid, docosahexaenoic acid (DHA). This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role as a bioactive metabolite and potential precursor in lipid signaling pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and manufacturers of high-purity biochemical standards and reference materials.

Application

• Biochemical Research Standard: Serves as a high-purity analytical reference standard for metabolic and lipidomic studies.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutics targeting inflammation and neurological pathways.
• Lipidomics & Metabolomics: A critical metabolite for profiling and understanding DHA metabolism and oxylipin pathways in biological systems.
• Nutritional Science Research: Investigated for its potential bioactive effects and role in human health as a metabolite of ω-3 fatty acids.
• Cell Signaling Studies: Employed in vitro and in vivo research to elucidate the mechanisms of specialized pro-resolving mediators (SPMs).
• Diagnostic Development: Potential use in calibrating assays for the quantification of oxylipins in clinical and research settings.

Basic Information

Product Name	11-Hydroxydocosahexaenoate
CAS No.	86360-68-1
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	11-HDHA; 11-Hydroxy-4,7,10,13,16,19-docosahexaenoic acid; 11-Hydroxy-DHA; (4Z,7Z,10Z,13Z,16Z,19Z)-11-Hydroxydocosa-4,7,10,13,16,19-hexaenoic acid; 11-HDoHE; 11-Hydroxydocosahexaenoic acid
EINECS	Contact for details

Quality Control

Our 11-Hydroxydocosahexaenoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC-MS, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We support research and development with materials suitable for use as analytical standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by GC or titration)
Solubility	Soluble in ethanol, DMSO, methanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.