Description

14-Hydroxydocosahexaenoic Acid (14-HDoHE) is a specialized, hydroxylated derivative of the essential ω-3 fatty acid DHA (docosahexaenoic acid). This compound is of significant interest in biochemical and pharmaceutical research due to its role as a bioactive lipid mediator involved in the resolution phase of inflammation. It is primarily utilized by research institutions and life science companies focused on inflammation, neurology, and metabolic pathways for developing novel therapeutic and diagnostic applications.

Application

• Biochemical Research: Used as a high-purity reference standard and analytical reagent in lipidomics and metabolomics studies.
• Pharmaceutical R&D: Serves as a key intermediate and active pharmaceutical ingredient (API) precursor in the development of novel anti-inflammatory and pro-resolving therapeutics.
• Cell Signaling Studies: Employed to investigate specialized pro-resolving mediator (SPM) pathways and their effects on cellular function.
• Nutraceutical Development: Explored as a potential bioactive component in advanced nutritional supplements targeting inflammatory responses.
• Academic Research: A critical tool for universities and research institutes studying the biochemistry of ω-3 fatty acids and their oxygenated metabolites.

Basic Information

Product Name	14-Hydroxydocosahexaenoic Acid
CAS No.	86360-66-9
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	14-HDoHE; 14-Hydroxy-4,7,10,12,16,19-docosahexaenoic acid; 14(S)-HDoHE; 14-Hydroxy-DHA; (4Z,7Z,10Z,12E,14S,16Z,19Z)-14-Hydroxydocosa-4,7,10,12,16,19-hexaenoic acid; 14-Hydroxydocosa-4,7,10,12,16,19-hexaenoic Acid; 14-HDHA
EINECS	Contact for details

Quality Control

Our 14-Hydroxydocosahexaenoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/GC-MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (Total)	≥ 98%
Solubility	Soluble in ethanol, DMSO, DMF; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.