Description

1-o-Hexadecyl-2-Arachidonyl-Sn-Glycero-3-Phosphocholine is a synthetic, chemically defined phospholipid analog, specifically an ether-linked phosphatidylcholine. This high-purity compound is critical for membrane biophysics research and the development of advanced lipid-based delivery systems, providing a stable and well-characterized alternative to natural, ester-linked phospholipids. It is primarily utilized by pharmaceutical R&D teams, academic researchers in cell biology, and manufacturers of liposomal formulations and diagnostic reagents.

Application

• Biophysical Research: As a key component in model membrane studies to investigate lipid raft formation, membrane fluidity, and protein-lipid interactions due to its defined ether-linked structure.
• Liposome & Nanoparticle Formulation: Used to create stable, oxidation-resistant liposomal bilayers for drug delivery, particularly for encapsulating sensitive active pharmaceutical ingredients (APIs).
• Cell Culture & Signaling Studies: Employed as a precursor or analog in studies of arachidonic acid metabolism and phospholipase A2 (PLA2) enzyme activity.
• Diagnostic Reagent Manufacturing: Serves as a raw material in the production of calibrators, controls, and reagents for clinical diagnostics.
• Pharmaceutical Reference Standard: Acts as a high-purity analytical standard for quality control and method development in lipidomics and related fields.

Basic Information

Product Name	1-o-Hexadecyl-2-Arachidonyl-Sn-Glycero-3-Phosphocholine
CAS No.	86288-11-1
Molecular Formula	C44H82NO8P
Molecular Weight	784.10 g/mol
Synonyms	1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine; C16:0-e/C20:4 PC; 1-O-Hexadecyl-2-arachidonoyl-phosphatidylcholine; Ether PC(16:0e/20:4); PAF C-16 Analogue; 1-Hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine; 1-O-Alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine; Synthetic Ether-Linked Phosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Arachidonyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and MS to confirm identity, purity, and lipid composition. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For custom grades or specific impurity profiles, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed vial under an inert atmosphere (argon or nitrogen) at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow it to reach room temperature in a desiccator before opening to prevent condensation. Once opened, purge the container with inert gas and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus)	≥ 98%
Solubility	Soluble in chloroform, ethanol; forms liposomes in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.