Description

1-Palmitoyl-2-(10-(4-((Trifluoromethyl)Diazirinyl)Phenyl)-8-Oxadecanoyl)-Sn-Glycero-3-Phosphocholine is a specialized, photoactivatable phospholipid derivative designed for advanced biochemical and biophysical research. This compound is a critical tool for studying membrane protein interactions, lipid dynamics, and cellular processes through covalent cross-linking upon UV light activation. It is primarily utilized by research scientists and pharmaceutical developers in the fields of structural biology, proteomics, and drug discovery.

Application

• Membrane Protein Labeling and Cross-linking for structural and functional studies.
• Lipidomics Research as a probe to investigate lipid-protein interactions within cellular membranes.
• Proteomic Analysis to identify and characterize proteins associated with specific lipid domains.
• Drug Discovery Platforms for target identification and validation of membrane-bound targets.
• Biophysical Studies including fluorescence quenching, FRET, and model membrane system assembly.
• Development of Diagnostic Assays and biosensors that rely on specific membrane anchoring.

Basic Information

Item	Detail
Product Name	1-Palmitoyl-2-(10-(4-((Trifluoromethyl)Diazirinyl)Phenyl)-8-Oxadecanoyl)-Sn-Glycero-3-Phosphocholine
CAS No.	86013-84-5
Molecular Formula	C₄₉H₇₆F₃N₄O₉P
Molecular Weight	965.11 g/mol
Synonyms	PC(16:0/Diazirine-Phenyl); TPD-PC; Photoactivatable Phosphatidylcholine; Diazirine-modified Phospholipid; 1-Palmitoyl-2-(10-(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)decanoyl)-sn-glycero-3-phosphocholine; Trifluoromethylphenyl Diazirinyl Phosphatidylcholine; Membrane Probe Lipid; Cross-linking Lipid Reagent
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-(10-(4-((Trifluoromethyl)Diazirinyl)Phenyl)-8-Oxadecanoyl)-Sn-Glycero-3-Phosphocholine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. All products undergo rigorous analytical testing, including HPLC and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). Due to its hygroscopic and strictly light-sensitive nature, the material should be handled in a controlled environment and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Assay (NMR)	≥ 90% (w/w)
Solubility	Soluble in chloroform, DMSO, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.