Description

1-o-(cis-9-Octadecenyl)-2-o-Acetyl-Sn-Glycero-3-Phosphocholine is a synthetic, structured phospholipid analog, specifically an acetylated alkylphosphocholine derivative. This compound is of significant value in advanced research and development due to its role as a key intermediate and model compound for studying membrane biophysics, lipid metabolism, and cell signaling pathways. It is primarily sought after by pharmaceutical researchers, academic institutions, and specialty chemical manufacturers working on liposomal drug delivery systems, lipidomics, and the development of novel bioactive lipids.

Application

• Lipidomics & Biomedical Research: Used as a standard or probe in mass spectrometry-based lipid analysis to understand lipid composition and metabolism in cells.
• Liposomal Drug Delivery: Serves as a functional excipient or a structural component in the formulation of advanced liposomes and nanoparticles for targeted therapeutic delivery.
• Membrane Biophysics Studies: Employed as a model lipid to investigate the properties of cell membranes, including fluidity, phase behavior, and protein-lipid interactions.
• Biochemical Reagent: Acts as a substrate or inhibitor in enzymatic assays, particularly those involving phospholipases and other lipid-modifying enzymes.
• Pharmaceutical Intermediate: Utilized in the synthetic pathway for developing novel phospholipid-based active pharmaceutical ingredients (APIs) or prodrugs.
• Cell Signaling Research: Investigated for its potential role in modulating intracellular signaling cascades related to the phosphocholine headgroup.

Basic Information

Product Name	1-o-(cis-9-Octadecenyl)-2-o-Acetyl-Sn-Glycero-3-Phosphocholine
CAS No.	85966-90-1
Molecular Formula	C28H56NO7P
Molecular Weight	549.72 g/mol
Synonyms	Oleyl PAF C-16; 1-O-(cis-9-Octadecenyl)-2-acetyl-sn-glycero-3-phosphocholine; 1-O-Octadec-9-enyl-2-acetyl-sn-glycero-3-phosphocholine; Alkylacetylphosphocholine; Acetyl Alkyl Lysophosphatidylcholine; 1-O-Alkyl-2-acetyl-sn-glycero-3-phosphocholine (Oleyl analog); PAF C-16:0/2:0 (Oleyl); Synthetic Platelet-Activating Factor Analog
EINECS	Contact for details

Quality Control

Every batch of 1-o-(cis-9-Octadecenyl)-2-o-Acetyl-Sn-Glycero-3-Phosphocholine is manufactured and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems ensure traceability and consistency, supporting research reproducibility and compliance with Good Laboratory Practice (GLP) standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single spot
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.