Description

H-Arg(No2)-Pna is a specialized nitro-arginine derivative peptide, widely utilized as a key synthetic intermediate and research chemical. Its primary value lies in its role as a protected arginine building block, essential for the controlled synthesis of complex peptides and peptidomimetics. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and biotechnology sectors, where it is used in drug discovery, proteomics research, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected arginine derivative for the controlled assembly of peptide chains.
• Pharmaceutical Research & Development: A key intermediate in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and enzyme studies to investigate arginine-related biological pathways and interactions.
• Peptidomimetic Design: Serves as a scaffold for creating non-peptide compounds that mimic the structure and function of natural peptides.
• Academic & Industrial Laboratories: A valuable reagent for chemical biology and medicinal chemistry projects.

Basic Information

Product Name	H-Arg(No2)-Pna
CAS No.	85697-89-8
Molecular Formula	C12H17N7O4
Molecular Weight	323.31 g/mol
Synonyms	NG-Nitro-L-arginine 4-nitroanilide; H-Arg(NO2)-pNA; L-Arginine, N2-[(4-nitrophenyl)amino]carbonyl]-, N5-(aminocarbonyl)-, NG-nitro-; Nitroarginine p-nitroanilide; Arg(NO2)-pNA; NO2-Arg-pNA; Peptide synthesis building block for protected arginine
EINECS	Contact for details

Quality Control

Our H-Arg(No2)-Pna is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent in-house specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.