Description

19-Hydroxysenecionine is a pyrrolizidine alkaloid derivative, a compound of significant interest in specialized chemical research and development. Its primary value lies in its role as a key intermediate or reference standard for the study of natural product chemistry and toxicology. This compound is essential for researchers and manufacturers in the pharmaceutical, phytochemical, and analytical chemistry sectors who require high-purity, well-characterized biochemicals for method development and safety assessments.

Application

• Phytochemical Reference Standard: Used as a certified standard for the identification and quantification of pyrrolizidine alkaloids in plant extracts and herbal products.
• Toxicology Research: Serves as a critical material in metabolic and hepatotoxicity studies to understand the bioactivation and safety profile of related alkaloids.
• Pharmaceutical Impurity Profiling: Employed in the development and validation of analytical methods to detect and control potentially genotoxic impurities in drug substances.
• Natural Product Synthesis: Acts as a sophisticated intermediate or building block in the semi-synthesis of complex alkaloids for biological screening.
• Quality Control in Herbal Supplements: Utilized by QC laboratories to ensure the absence or safe limits of hepatotoxic pyrrolizidine alkaloids in consumer health products.
• Academic and Institutional Research: Supports fundamental research in chemical ecology, plant biochemistry, and medicinal chemistry at universities and R&D institutes.

Basic Information

Item	Detail
Product Name	19-Hydroxysenecionine
CAS No.	85611-43-4
Molecular Formula	C18H27NO7
Molecular Weight	369.41 g/mol
Synonyms	19-Hydroxysenecionine; Senecionine-19-ol; 12-Hydroxysenecionan-11,16-dione; (1R,4R,7S,8R,13S,14R,17R)-4,7-Dihydroxy-8-(hydroxymethyl)-14-methyl-3,11,16-trioxo-2,6,9,15-tetraazatetracyclo[10.5.1.0¹,¹³.0⁴,⁸]octadec-17-yl 3-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Every batch of 19-Hydroxysenecionine is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results from techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.